chicken erythrocyte nuclei were allowed to decondense in a low salt high pH buffer, fixed with HCOH, centrifuged onto a carbon coated EM grid, and stained with uranyl acetate. (Spreading technique of ...

Image shows a z-series immuno-FISH of a mouse ES cell carrying a multi-copy alpha-globin BAC insertion: HP1 gamma immunostaining (blue) is shown relative to BAC FISH signal (red) versus combined lac o...

This animation shows a nucleosome located in its putative binding site on the SWI-SNF remodeling complex from yeast. The atomic structure of the DNA component of the nucleosome based on x-ray diffrac...

TEM image of frozen hydrated soluble chromatin isolated from COS-7 cells and vitrified in 15 mM monovalent ions. The chromatin adopts an irregular zigzag fiber conformation. See Fig 2 in J Bednar et ...

Transmission electron micrograph of nucleus showing the characteristic features of glutaraldehyde fixation introduced as a primary fixative in 1962 and since used routinely. Chromatin appears differen...

Image shows an immuno-FISH z-series of a mouse ES cell carrying a multi-copy insertion of alpha-globin BAC showing partial co-localization of lac operator FISH signal (green) with H3K9me3 immunostaini...

z-series image of 3D immuno-FISH of multi-copy alpha-globin BAC insertions in a mouse ES cell. Immunostaining of HP1alpha (blue) is shown versus FISH signals against total BAC sequence (red) or combi...

TEM image of frozen hydrated soluble chromatin isolated from chicken erythrocyte nuclei and vitrified in low salt. Polynucleosomes adopt an irregular zigzag fiber conformation (a,b,k), and show a 'ste...

Nucleated erythrocytes from chicken were spread on water, the dispersed chromatin picked up on carbon-formvar grids, fixed with paraformaldehye, critical point dried and shadowed with platinum. Image...

Nucleated erythrocytes from chicken were spread on water, the dispersed chromatin picked up on carbon-formvar grids, fixed with paraformaldehye, critical point dried and shadowed with platinum. Image...