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Cell Process
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Alzheimer's
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University of California, San Diego
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CIL:13878
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
cytokinesis
Cellular Component
spindle pole body
During late anaphase, Tem1 (green) localized to the spindle pole body (SPB) in cdc15-2 bfa1Δ cells grown at the restrictive temperature. DAPI (blue) and DIC (hidden) are also shown. Compare to image ...
CIL:13882
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
regulation of exit from mitosis
Cellular Component
nucleus
Tem1 normally localizes preferentially to the spindle pole body (SPB) that enters the daughter cell during anaphase (this image and CIL# 13885). This image shows SPB localization of eGFP-Tem1 (eGFP, g...
CIL:13883
NCBI Organism Classification
Saccharomyces cerevisiae
Biological Process
regulation of exit from mitosis
Cellular Component
nucleus
Constitutive targeting of Tem1 to the spindle pole body (SPB) in metaphase cells (this image) and anaphase cells (CIL#13886). tem1Δ::GAL-UPL-TEM1 cells expressing eGFP-CNM67–TEM1 from a CEN plasmid...
CIL:13679
NCBI Organism Classification
Drosophila melanogaster
Biological Process
response to wounding
Cellular Component
nucleus
The JNK phosphatase puckered, whose expression can be reported via a lacZ enhancer trap, is expressed in very low levels in uninjured neurons; however, nerve crush induces a dramatic increase in puc-l...
CIL:13681
NCBI Organism Classification
Chlorocebus aethiops
Biological Process
protein targeting to plasma membrane
Cellular Component
integral to plasma membrane
To study the cellular consequences of misfolding of plasma membrane proteins, a transmembrane model protein that was constitutively targeted to the plasma membrane was developed for use as a reporter ...
CIL:13684
NCBI Organism Classification
Chlorocebus aethiops
Biological Process
protein targeting to plasma membrane
Cellular Component
integral to plasma membrane
To study the cellular consequences of misfolding of plasma membrane proteins, a transmembrane model protein that was constitutively targeted to the plasma membrane was developed for use as a reporter ...
CIL:13693
NCBI Organism Classification
Homo sapiens
Biological Process
receptor internalization
Cellular Component
plasma membrane
This is one of six images in Figure 6 in Apaja et al., JCB 2010 that shows the fate of various model membrane proteins, that are either folded or in the unfolded state at the plasma membrane, expresse...
CIL:13700
NCBI Organism Classification
Chlorocebus aethiops
Biological Process
G-protein coupled receptor internalization
Cellular Component
plasma membrane
This is one of a group of four images in Figure S5 in Apaja et al., JCB 2010, that support the conclusion that the WT vasopressin type2 receptor (V2R) and the V2R W164S mutant (that causes nephrogenic...
CIL:13708
NCBI Organism Classification
Homo sapiens
Biological Process
mitochondrion degradation
Cellular Component
mitochondrion
YFP-Parkin (green) does not translocate to mitochondria (red) when HeLa cells are transfected with control siRNA (siCtrl). HeLa cells stably expressing YFP-Parkin were transfected with control siRNA f...
CIL:13718
NCBI Organism Classification
Homo sapiens
Biological Process
protein targeting to mitochondrion
Cellular Component
mitochondrion
PINK1-YFP R98F (green) is localized to mitochondria in the absence of the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone). The R98F mutation in PINK1-YFP partially in...
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