Image shows an immuno-FISH z-series of a mouse ES cell carrying a multi-copy insertion of alpha-globin BAC showing partial co-localization of lac operator FISH signal (green) with H3K9me3 immunostaini...

z-series image of 3D immuno-FISH of multi-copy alpha-globin BAC insertions in a mouse ES cell. Immunostaining of HP1alpha (blue) is shown versus FISH signals against total BAC sequence (red) or combi...

Z-series image of mouse ES cells carrying a beta-globin BAC transgene array (clone 8d) and transduced with a lentivirus containing an EGFP-lacI expression cassette. EGFP-LacI binding (green) to the 25...

Z-series image of mouse ES cells carrying an alpha-globin BAC transgene array (clone 7d) transduced with a lentivirus containing an expression cassette for EGFP-LacI. EGFP-LacI binding (green) to the...

Z-series images of mouse ES cells carrying DHFR BAC transgene array (clone 36) and differentiated into fibroblast-like cells. 3D FISH shows increase in number of lac operator foci (green) and change ...