A representative untreated drs2Δ mutant cell. DRS2 encodes an aminophospholipid flippase that regulates phospholipid asymmetry. (10,000X). CIL 40424 is a sertraline-treated drs2∆ mutant cell.
This group of images contains representative whole-cell images and high-magnification zooms of organelle structures of interest. All cells were grown in liquid rich media (YPD pH6.5) at 30C with aerated shaking, and cultures were sampled in mid-logarithmic phase. Treated cells were exposed to 60µM antidepressant sertraline (Zoloft®) for 45 minutes.
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