Transmission electron micrograph showing a mature autophagosome from a prototrophic wildtype cell treated with 60µM sertraline. Notice the inner membrane of the autophagosome is tubulating inward in two spots. (31,500X). CIL 40413 another image of a similarly treated cell.
This group of images contains representative whole-cell images and high-magnification zooms of organelle structures of interest. All cells were grown in liquid rich media (YPD pH6.5) at 30C with aerated shaking, and cultures were sampled in mid-logarithmic phase. Treated cells were exposed to 60µM antidepressant sertraline (Zoloft®) for 45 minutes.
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