Transmission electron micrograph of a thin section of the nucleus of a HeLa cell expressing a mutant of the nuclear porin ALADIN. The nuclear envelope ultrastructure is not affected by the mutation. Other images in this group show details of nuclear pore structure in cross section and tangential section.
Normal HeLa cells expressing were fixed with glutaraldehyde, embedded in epoxy resin, thin sectioned, and imaged using a Philips CM10 TEM. See: J Cronshaw and M Matunis 2003 The nuclear pore complex ALADIN is mislocalized in triple A syndrome Proc Natl Acad Sci USA 100 5823-5827
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