Transmission electron micrograph of a thin section of the nucleus of a HeLa cell expressing mutant ALADIN. Pore structure appears to be unaffected in the mutant. From a study of the role of the nuclear porin ALADIN. Other images in this group show additional details of nuclear pore structure in normal and mutant cells.
Normal HeLa cells expressing were fixed with glutaraldehyde, embedded in epoxy resin, thin sectioned, and imaged using TEM. See: J Cronshaw and M Matunis 2003 The nuclear pore complex ALADIN is mislocalized in triple A syndrome Proc Natl Acad Sci USA 100 5823-5827
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