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Description
Transmission electron micrograph showing the extensive accumulation of darkly stained heterochromatin at the nuclear periphery typical of many differentiated cells. Heterochromatin is excluded from regions of nuclear envelope with nuclear pores. This organization is illustrated here in a bone marrow plasma cell from guinea pig. Figure 114 from Chapter 4 (Nucleus) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the corresponding chapter is available on the ASCB's BioEDUCATE website.
Biological Sources
- NCBI Organism Classification
- Cavia porcellus
- (Guinea Pig)
- Cell Type
- plasma cell
- Cellular Component
- nuclear heterochromatin
- nucleolus
- nuclear envelope
- chromatin
- endoplasmic reticulum
Biological Context
- Biological Process
- nucleus organization
- nucleolus organization
- chromatin organization
Attribution
- Name
- Don W. Fawcett
- Published
- ISBN 0721635849
- from: Don W. Fawcett M.D ‘The Cell' 2nd edition, W.B. Saunders Chapter 4 (Nucleus)
- Link
- ASCB BioEDUCATE Program
Grouping
This image is part of a group.Imaging
- Image Type
- film
- Imaging Mode
- transmission electron microscopy (TEM)
- detection of electrons
- Parameters Imaged
- electron density
- Source of Contrast
- differences in adsorption or binding of stain
- Visualization Methods
- uranyl salt
- osmium tetroxide
- lead salt
- Processing History
- Image extracted from .pdf file of 'The Cell'
- Data Qualifiers
- processed data
Sample Preparation
- Methods
- tissue in plastic embedment
- osmium tetroxide fixed tissue
- glutaraldehyde fixed tissue
- Relation To Intact Cell
- microtome-sectioned tissue
Dimensions
| Spatial Axis | Image Size | Pixel Size |
|---|---|---|
| X | 887px | —— |
| Y | 1272px | —— |
*CIL – Cell Image Library accession number. Please use this to reference an image.