Transmission electron micrograph of the salivary gland of the tick Rhipicelphals appendiculatus illustrating the dramatic difference in nuclear size seen in different cell types. Here, the large (probably polyploid or polytene) nucleus of the glandular cell contrasts with the small epithelial cell at lower right. Figure 109 from Chapter 4 (Nucleus) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A PDF copy of the corresponding chapter is available on the ASCB's BioEDUCATE website.