Isolated mitochondria that have been quick-frozen, fractured and deep-etched show some space between the inner and outer membranes. Arcs of tubules, where they are tangentially fractured, show the hel...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein hPrp4 and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The hPrp4 is confined to the nu...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein hPrp8 and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The hPrp8 is confined to the nu...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein U1-70K-GFP and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The U1-70K-GFP is confined...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein U1-70K lacking the RNA-binding residues 1-197 and imaged witb a PicoQuant MicroTime 200 confocal microscope using an Olympus 60x 1.2N...

HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein U1-70K and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The U1-70K protein is confined...

HeLa cells stably expressing the BAC-encoded GFP-labeled hPrp8 snRNP and MS2-mRED protein and treated with doxycholine to express the E3 transgene. Shown is the GFP signal. Cells imaged witb a Leica ...

HeLa cells stably expressing the BAC-encoded GFP-labeled hPrp4 snRNP and MS2-mRED protein and treated with doxycholine to express the E3 transgene. Shown is the mRED signal. Cells imaged witb a Leica...

HeLa cells stably expressing the BAC-encoded GFP-labeled U170K snRNP and MS2-mRED proteins and treated with doxycholine to express the E3 transgene. Shown is the mRED signal. Cells imaged witb a Leic...

HeLa cells stably expressing the BAC-encoded GFP-labeled U2B snRNP and Ms2-mRED protein and treated with doxycholine to express the E3 transgene. Shown is the MS2-mRED signal. Cells imaged witb a Lei...